Largest human heart bank advances understanding of heart failure

Australian researchers have made several new heart failure discoveries in an innovative world-first project examining cryo-preserved human hearts, procured after transplantation, in the Sydney Heart Bank. Scientists at the University of Sydney’s Charles Perkins Centre and the Heart Research Institute studied the molecules in hearts removed at the time of transplantation, revealing what happens inside […]

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Presence of parasite infection closely linked to the make-up of the gastrointestinal microbiome

Parasite infections are a constant presence for many people who live in tropical regions, particularly in less industrialized areas. These often chronic conditions are at best unpleasant; more seriously, children with parasite diseases that cause diarrhea can die of malnutrition or dehydration. In Genome Biology, a study led by University of Pennsylvania scientists investigated the […]

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New cell therapy approaches yield fewer complications after organ transplantation

A large international study coordinated by University Hospital Regensburg and Charité – Universitätsmedizin Berlin has demonstrated the safety of new cell therapy approaches for use in kidney transplant recipients. Transplant recipients were shown to require lower levels of immunosuppression in order to prevent organ rejection. This reduces the risk of side effects such as viral […]

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Lack of mitochondria causes severe disease in children

Researchers at Karolinska Institutet in Sweden have discovered that excessive degradation of mitochondria, the power plants of cells, plays an important role in the onset of mitochondrial disease in children. These inherited metabolic disorders can have severe consequence such as brain dysfunction and neurological impairment. The study is published in EMBO Molecular Medicine. “This is […]

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